Mayur Deshpande
  Personal trainer in Mumbai
Articles Human growth hormone

Article

Human growth hormone

HGH Human growth hormone, somatropin (Effective dose - 4 TO 6 IU per day)

HGH available in market is a synthetic derivative of natural Human growth hormone. (In the body) Human growth hormone is produced by somatotrophe cell in the pituitary gland. This gland is located in the center of the brain. HGH is made up of 191 amino acids - making it fairly large for a hormone. It is now important to understand that the freed HGH (human growth hormone) itself has no direct effect but only stimulates the liver to produce and release insulin like growth factors. These growth factors are then the ones that cause various effects on the body HGH secretion reaches its peak in the body during adolescence. As we get older our body produces less amounts of growth hormone. It's produced naturally in your body, but amounts decrease as you get older. Our body continues to produce human growth hormones usually in short bursts during deep sleep.
Athletes could attract to HGH because of the benefits associated with it. Benefits of synthetic HGH includes
1) it can not be detected in doping test 2) It stimulates hyperplasia (increase in the number of muscle cell) not just hypertrophy (increase in the size of muscle cell). 3) Rate of protein synthesis and utilization of fats increases.4) it strengthens the connective tissue, tendons, and cartilages, which could be one of the main reasons for the significant increase in strength experienced by many.
Daily dose is required in HGH cycle because it has a very short life span in the body.Adminstration of HGH should be in the morning because body produces its own HGH in night (when we sleep).Injectable form of HGH is more effective than oral, spray and gel.HGH injections are given subcutaneously. Bodybuilders stack HGH with thyroid hormone, anabolic and insulin. Side effects of HGH includes but not limited to Hypoglycemia, acromegaly, enlargement of heart and kidney. Acromegaly (Giantism) is only possible if HGH is used during the pre-pubescent (app. before 13 yrs) period time in ones life. These side effects are extremely rare. But when you wonder why some bodybuilders have huge, definitive abdominal muscle with around 4-5 % body fat yet they have large and protruding gut (abdominal section)? Reason is, when human growth hormones are injected to the body's skeletal muscle, it also has tendency to grow internal hormones like liver, heart & kidney.
It is always safe to optimize the natural secretion of human growth hormone. Natural Growth hormone secretion can be triggered by a number of natural stimuli, the most powerful of which are sleep and exercise. Various researchers have suggested that it could be triggered by exercise-induced increases in adrenaline, nitric oxide, blood lactate, acidity or nerve activity, either individually or together. It is vital for athletes to get plenty of sleep. It has also been shown that ingestion of 1.5g of Arginine (type of protein) will increase human growth hormone (HGH) secretion by blocking release of the HGH-inhibitor Somatostatin. In terms of training, research has shown that to achieve an elevation of human growth hormone (HGH) above baseline you need to spend at least 10 minutes training at above lactate threshold intensity. Both BCAA (Branch chain amino acids) and Glutamine (Protein) also have been shown to independently increase H.G.H. levels with dosages as low as 3 grams. By using 3-5 grams of each in between meals and an additional 5-10 grams glutamine before bed, athletes-especially those over the age of 30-may benefit by increased levels of GH. This in turn may lead to less body fat, greater energy and increased recovery from training.
HGH, when taken alone, is considerably less effective and can only reach its optimum effect by the additive intake of steroids, thyroid hormones, and insulin, in particular. But we must point out in this case that HGH has a predominately anabolic effect. There are three hormones which are needed at the same time in order to allow for maximum anabolic effect. These are HGH, insulin, and an LT-3 thyroid hormone, such as, for example, Cytomel. Only then can the liver produce and release an optimal amount of somatomedin and insulin-like growth factors. This anabolic effect can be further enhanced by taking a substance with an anticatabolic effect. Then a synergetic effect takes place.
Few athletes are still not happy about HGH result .The reasons few athletes talk ill about HGH is because 1)they have tried HGH during preparation for a competition in that phase when the diet is calorie-reduced. The body usually reacts by reducing the release of insulin and of the L- T3 thyroid hormone. And this is not an advantageous condition when HGH is expected to work well. Well, we almost forgot. Those who combine Clenbuterol with HGH should know that Clenbuterol (like Ephedrine) reduces the body's own release of insulin and L-T3, yes that is true. HGH has a significant influence on several hormones in the human body; this does not allow for a simple ad-ministration schedule. As said, HGH is not cheap and those who intend to use it should know a little more about it. 2) In a very few cases the body reacts by developing-antibodies to the exogenous HGH, thus making it ineffective.3) Most of the available HGH in black market are counterfeit.4) HGH when taken alone, is considerably less effective and can only reach its optimum effect by the additive intake of steroids, thyroid hormones, and insulin, in particular. There are three hormones which are needed at the same time in order to allow for maximum anabolic effect. These are HGH, insulin, and an LT-3 thyroid hormone.5) Last reason is ,being the most expensive drug, very few rich athletes could manage to us it in a sufficient amount regularly and over a long enough period of time. Although Growth Hormone is banned by athletic committees, there is no method for the detection of it which allows drug tested competitors to use this product freely without any ramifications.


IGF-1 (Insulin like growth factor-1) (Effective dose- 20-100 mcg per day)

IGF-1 (Insulin-Like Growth Factor) is a hormone that is naturally produced from HGH (Human Growth Hormone) in the liver.HGH converted into IGF-1 by the liver. Although insulin is involved in IGF-1 production, HGH is the primary precursor. It contains only 70 amino acids. It is more powerful then HGH. IGF-1 does have an effect on insulin production in the body. It will lead to a decrease in insulin secretion which at the same time increases insulin sensitivity. IGF-1 is chemically the same as insulin but it is also somewhat different. IGF-1 does not seem to regulate glucose levels in the body like insulin does though. As we age; the body secretes less HGH, and therefore IGF-1. IGF-1 belongs to same family of hormone as insulin. Bodybuilders took interest in IGF-1 because it offers lot of benefits. IGF-1 stimulates hyperplasia (increase in the number of muscle cell) not just hypertrophy (increase in the size of muscle cell).It stimulates protein synthesis and muscle growth.IGF-1 also promotes fat loss.IGF-1 injections are given as an intramuscular. Injectable form of HGH is more effective than oral, spray and gel.
Side effects of HGH includes but not limited to Carpel tunnel syndrome, Edema, Acromegaly, Gynecomastia and hypoglycemia. We always wonder why some bodybuilders have huge, definitive abdominal muscle with around 4-5 % body fat yet they have large and protruding gut (abdominal section)? Reason is, when human growth hormones are injected to the body's skeletal muscle, it also has tendency to grow internal hormones like liver & kidney
It is only made by three pharmaceutical companies in the world.