Nutritional Supplements Library
Glycomacropeptides
 

What is Glycomacropeptide?

Glycomacropeptide is a carbohydrate-rich casein peptide. This peptide is released by rennet during the manufacture of cheese or rennet casein. GMP is present at 10-15% in milk whey as a result of the action of the same enzyme during the cheesemaking process. It is rich in sialic acid, which studies show may influence digestive function and promote the growth of bifidobacteria. GMP preparations are also a source of peptide bound sialic acid, which has an involvement in brain development in the newborn and an anti-infective role in the small intestine.GMP are entirely lost in the ion-exchange method of production, resulting in an inferior product in terms of full potential benefits.Glycomacropeptides contain no aromatic amino acids and no phenylalanine. This makes GMP suitable for diets in the treatment of patients with phenylketonuria.Purified GMP and GMP-rich whey protein concentrates are currently available in market. This product is sometimes also called Caseinmacropeptide (CMP).


How does Glycomacropeptide form?

Whey protein is obtained from milk from one of the initial steps in the process of making cheese. During this process, one of the milk proteins, called casein (kappa casein) is split. GMP is the resulting composition of a certain amino acid sequence from this product. GMP supplementation has been shown to increase levels of cholecystokinin, a stomach secretion that plays a role in regulating feelings of fullness. GMP also may help to prevent dental cavities, and protect against viruses and bacteria.


What are the benefits of Glycomacropeptide supplementation?

  • GMP reduces dental caries and plaque by inhibiting the adhesion of tartar to teeth.
  • It may increase absorption of calcium, iron, or zinc.
  • It has been shown to promote lean muscle development
  • It is very high in branched amino acids (BCCA).
  • It also has bacterial toxin binding effect.
  • It controls intestinal health, by preventing stomach disorders caused by bacteria and viruses.
  • It lowers the risk of heart attack and stroke by inhibiting platelet aggregation and binding of I-fibrinogen to platelets.
  • It Prevents heartburn by reducing gastric acid secretion by as much as 53%.
  • It Suppress appetite by stimulating the release of cholecystokinin (CCK), a hormone that signals the brain of fullness.

What are the side effects of Glycomacropeptide supplementation?

They are no known adverse effects of glycomacropeptide.


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